Haematogenous cytokeratin 20 mRNA as a predictive marker for recurrence in oral cancer patients

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[Cytokeratin 20 as a marker of tumor progression or dissemination in patients with colorectal cancer].

BACKGROUND Colorectal cancer relapses or metastasizes in 30% of cases. Cytokeratin 20 is present in 95% of colorectal tumors and their metastases and could be used as a marker to detect tumor cells. AIM To assess the usefulness and prognostic value of peripheral blood and bone marrow cytokeratin 20 determinations in patients with colorectal cancer. MATERIAL AND METHODS Blood and bone marrow...

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Cytokeratin 17 mRNA as a prognostic marker of oral squamous cell carcinoma

Despite diagnostic and therapeutic advances, the 5-year survival rate of oral squamous cell carcinoma (OSCC) remains between 70-80% due to recurrences and secondary metastases to cervical lymph nodes. It is difficult to find these recurrences and metastases postoperatively, thus, careful follow-up is recommended. Cytokeratins (CKs) are intermediate filaments of the cytoskeleton and candidate pr...

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BACKGROUND The identification of rectal cancer patients predisposed to developing recurrent disease could allow directed adjuvant therapy to improve outcomes while decreasing unnecessary morbidity. This study evaluates carcinoembryonic antigen cellular adhesion molecule-7 (CEACAM-7) expression in rectal cancer as a predictive recurrence factor. METHODS A single-institution colorectal cancer d...

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High expression of miR-181c as a predictive marker of recurrence in stage II colorectal cancer

INTRODUCTION A standard treatment for stage II colorectal cancer (CRC) is surgical resection without adjuvant chemotherapy. However, the recurrence rate of these patients is approximately 20%. To date, there are no robust biomarkers suitable for predicting recurrence in stage II CRC patients. In this study, microRNAs (miRNAs) extracted from CRC tissues were examined for a possible biomarker to ...

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ژورنال

عنوان ژورنال: British Journal of Cancer

سال: 1999

ISSN: 0007-0920,1532-1827

DOI: 10.1038/sj.bjc.6690377